Abdelrahman S. Mayhoub, Ph.D
ACADEMIC TITLE
Associate Professor
Nano Sciences
Zewail City for Science and Technology
NB, F009
Contact Information
Education: Doctor of Philosophy degree in Medicinal Chemistry & Molecular Pharmacology from Purdue University, IN, U.S. in 2012
Research Areas: Synthetic chemistry, Organometalics, Medicinal chemistry and Pharmacokinetics
Research Interests: Development of new antibiotics for beating extremely-drug resistant pathogens; pharmacokinetics-based drug design; controlling the pharmacokinetic behavior of bio-active molecules; development of novel methodology for C-C and C-N bonds
Keywords: Phenylthiazoles, UppP, UppS, MDR-bacteria
Positions: Associate Professor at Nanoscience Program
1) Kotb, M et al. tert-Butylphenylthiazoles with Oxadiazole Linker: Novel Orally Bioavailable Class of Antibiotics with Anti-Biofilm Activity RCS Advances, 2019, 9, 6770
2) Hagras, M.et al. Naphtylthiazoles: Targeting multidrug-resistance Staphylococcus aureus with biofilm disruption activities ACS Infect Dis, 2018, 4, 1679
3) ElAwamy, M. et al. Alkoxyphenylthiazoles with Broad-Spectrum Activity Against Multi-Drug Resistant Gram-Positive Bacterial Pathogens Eur. J. Med. Chem. 2018, 152, 318
4) Ngo, H. et al. Potent 1,2,4-triazinoindole-3-thioether inhibitors of the kanamycin resistance enzyme Eis from Mycobacterium tuberculosis ACS Infect Dis. 2018, 4, 1030
5) Hagras, M. et al. Investigating the Antibacterial Activity of Biphenylthiazoles Against Methicillin- and Vancomycin-Resistant Staphylococcus aureus (MRSA and VRSA) J. Med. Chem. 2017, 60, 4074
1) Towards Expanding the Antibacterial Spectrum of Phenylthiazole Antibiotics , ASRT
2) US-Egypt Joint Grant, Development of Next Generation Arylthiazoles for Combating Methicillin & Vancomycin Resistant Staphylococcus Aureus, STDF
3) Design and Synthesis of Liver Targeting Ribavirin Nanoparticle Conjugates; Science and Technology Development Fund (STDF-Egypt);
1) Egyptian State Encouragement Award in Medical Research
2) First-Class Excellence Medal from Presidential Office, August 2017
3) Young Arab Scientist (YAS) Prize in 2014 from TWAS-ARO (The World Academy of Sciences for the Advancement of Science in Developing Countries – Arab Regional Office).
4) Patents: US Patent App. 15/973,569, 2018; US Patent 9,801,861, 2017; US. PCT/US 2014/0121249 A1; US. PCT/US 2012/024706 and WO 2,012,109,573 A1 20120816.