Doxorubicin is among the most commonly used chemotherapeutic agents for treatment of various types of tumors because of its high potency against cancer cells and its relatively low cost. However, its use for the treatment of brain tumors was not possible because of the blood brain barrier which prevents completely any hydrophilic drugs as doxorubicin from reaching the brain.
Innovative Technology for Drug Delivery for the Treatment of Eye Diseases and as an Alternative to Traditional Methods
Many ophthalmology patients face some problems that are related to the usage of eye drops. Many patients, for instance, do not recognize that the eye drops may lose their efficiency a few weeks after its opening or due to inconvenient storage. In addition, some studies proved that only 5% of the dose reaches the patient, as he/she loses around 95% of the dose during the administration due to the low viscosity of the eye drops.
Center for Genomics Publishes a New Article Entitled: Choose your Yeast Strain Carefully: the RAD5 Gene Matters
The article addresses a very important issue that was not properly handled previously. Budding yeast has been established as a model organism to study cellular processes for decades.
Considered as a great success in their fields, both researches have been conducted in the Center for Materials Science in Zewail City by the in house team of researchers and under the leadership of Dr. Mohamed Alkordi, head of the Egyptian research team at Zewail City of Science and Technology, along with significant contribution from other local and international affiliations.
Dementia and Motor neuron disease (MND) are among the most common neurodegenerative disorders in Egypt, affecting people in the middle of their active life.
Work led by Dr Sherif El-Khamisy, Director of the Center of Genomics at Zewail City & Chair of Molecular Medicine at the University of Sheffield, in collaboration with the University of Sussex, University of Newcastle and St Jude hospital in the US unravels the mystery of DNA attacks in cells’ powerhouse - the mitochondria - providing novel avenues to tackle neurodegenerative diseases and cancer.
Dr. Muhammed Amin, Assistant Professor at the Center for Photonics and Smart Materials in Zewail City of Science and Technology with a team of researchers from different research labs has published a scientific paper in Nature Methods in the field of x-ray free-electron lasers.
In an interdisciplinary initiative led by Prof. Ibrahim El-Sherbiny, Joint Director of the Center for Materials Science (CMS) in collaboration with the Center for Nanotechnology (CNT) at Zewail City for Science and Technology, researchers developed a promisingrapid, and highly efficient electrochemical biosensor mainly used for quantitative analysis of glucose concentration in patients’ blood samples.
Researchers used gold nanoparticles (AuNPs) and HCV's specific genomic signature
The researchers discovered that a specific modification in a protein called histone that wraps the DNA made repair much faster in cancer cells, which resulted in therapy resistance.
A novel pathway to immobilize gold (Au) nanoparticles within microporous organic polymers
A Novel Way to Construct Graphene-porous Organic Polymer Composite for Electrocatalytic Conversion of CO2
Researchers combined graphene and POP for application in the electrocatalytic conversion of CO2
Researchers encapsulated Silymarin in nano-sized particles
Zewail City: Innovative Porous Polymers for Photochemical Catalytic Applications in Energy and Environment
Development of novel pathway to construct platform solids for applications in photochemical heterogeneous catalysis.
Novel therapeutic nano-formulation with potential for treating pulmonary arterial hypertension (PAH).