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1Ismail, M. A., Negm, A., Arafa, R. K., Abdel-Latif, E. & El-Sayed, W. M. Anticancer activity, dual prooxidant/antioxidant effect and apoptosis induction profile of new bichalcophene-5-carboxamidines. European Journal of Medicinal Chemistry 169, 76-88, doi:10.1016/j.ejmech.2019.02.062 (2019).

2El-Zahabi, H. S. A. et al. New thiobarbituric acid scaffold-based small molecules: Synthesis, cytotoxicity, 2D-QSAR, pharmacophore modelling and in-silico ADME screening. European Journal of Pharmaceutical Sciences 130, 124-136, doi:10.1016/j.ejps.2019.01.023 (2019).

3Abdelhafez, O. M. et al. Design and molecular modeling of novel P38α MAPK inhibitors targeting breast cancer, synthesized from oxygen heterocyclic natural compounds. Bioorganic and Medicinal Chemistry, doi:10.1016/j.bmc.2019.02.027 (2019).

4Sedky, N. K. et al. The molecular basis of cytotoxicity of α-spinasterol from Ganoderma resinaceum: Induction of apoptosis and overexpression of p53 in breast and ovarian cancer cell lines. Journal of Cellular Biochemistry 119, 3892-3902, doi:10.1002/jcb.26515 (2018).

5Mohammad, H. et al. Discovery of a Novel Dibromoquinoline Compound Exhibiting Potent Antifungal and Antivirulence Activity That Targets Metal Ion Homeostasis. ACS Infectious Diseases 4, 403-414, doi:10.1021/acsinfecdis.7b00215 (2018).

6Abo-Elmagd, N. E., George, R. F., Ezzat, M. A. & Arafa, R. K. New 1-phthalazinone scaffold based compounds: Design, synthesis, cytotoxicity and protein kinase inhibition activity. Mini-Reviews in Medicinal Chemistry 18, 1759-1774, doi:10.2174/1389557518666180903153254 (2018).

7Ismail, M. A., Youssef, M. M., Arafa, R. K., Al-Shihry, S. S. & El-Sayed, W. M. Synthesis and antiproliferative activity of monocationic arylthiophene derivatives. European Journal of Medicinal Chemistry 126, 789-798, doi:10.1016/j.ejmech.2016.12.007 (2017).

8Elghazawy, N. H., Hefnawy, A., Sedky, N. K., El-Sherbiny, I. M. & Arafa, R. K. Preparation and nanoformulation of new quinolone scaffold-based anticancer agents: Enhancing solubility for better cellular delivery. European Journal of Pharmaceutical Sciences 105, 203-211, doi:10.1016/j.ejps.2017.05.036 (2017).

9Arafa, R. K. & Elghazawy, N. H. in Advances in Experimental Medicine and Biology Vol. 1007   199-224 (2017).

10Youssef, M. M., Arafa, R. K. & Ismail, M. A. Synthesis, antimicrobial, and antiproliferative activities of substituted phenylfuranylnicotinamidines. Drug Design, Development and Therapy 10, 1133-1146, doi:10.2147/DDDT.S102128 (2016).

11Ghorab, M. M. et al. NAD(P)H: Quinone oxidoreductase 1 inducer activity of some novel anilinoquinazoline derivatives. Drug Design, Development and Therapy 10, 2515-2524, doi:10.2147/DDDT.S105423 (2016).

12Ghorab, M. M. et al. Synthesis, molecular modeling and NAD(P)H:quinone oxidoreductase 1 inducer activity of novel 2-phenylquinazolin-4-amine derivatives. Journal of Enzyme Inhibition and Medicinal Chemistry 31, 1612-1618, doi:10.3109/14756366.2016.1158714 (2016).

13Eldebss, T. M. A., Farag, A. M., Abdulla, M. M. & Arafa, R. K. Novel benzoimidazole-based heterocycles as broad spectrum anti-viral agents: Design, synthesis and exploration of molecular basis of action. Mini-Reviews in Medicinal Chemistry 16, 67-83 (2016).

14El Sayed, N. A., Eissa, A. A., El Masry, G. F., Abdullah, M. & Arafa, R. K. Discovery of novel quinazolinones and their acyclic analogues as multi-kinase inhibitors: design, synthesis, SAR analysis and biological evaluation. RSC Advances 6, 111767-111786, doi:10.1039/C6RA19137A (2016).

15Eldebss, T. M. A., Gomha, S. M., Abdulla, M. M. & Arafa, R. K. Novel pyrrole derivatives as selective CHK1 inhibitors: Design, regioselective synthesis and molecular modeling. MedChemComm 6, 852-859, doi:10.1039/c4md00560k (2015).

16Eldebss, T. M. A., Gomha, S. M., Abdulla, M. M. & Arafa, R. K. Erratum: Novel pyrrole derivatives as selective CHK1 inhibitors: Design, regioselective synthesis and molecular modeling (MedChemComm (2015)). MedChemComm 6, 977, doi:10.1039/c5md90016f (2015).