Abdelrahman S. Mayhoub, Ph.D


Associate Professor

Nano Sciences

Zewail City for Science and Technology

NB, F009

Contact Information




Education: Doctor of Philosophy degree in Medicinal Chemistry & Molecular Pharmacology from Purdue University, IN, U.S. in 2012

Research Areas: Synthetic chemistry, Organometalics, Medicinal chemistry and Pharmacokinetics

Research Interests: Development of new  antibiotics for beating extremely-drug resistant pathogens; pharmacokinetics-based drug design; controlling the pharmacokinetic behavior of bio-active molecules; development of novel methodology for C-C and C-N bonds

Keywords: Phenylthiazoles, UppP, UppS, MDR-bacteria

Positions: Associate Professor at Nanoscience Program

1) Kotb, M et al. tert-Butylphenylthiazoles with Oxadiazole Linker: Novel Orally Bioavailable Class of Antibiotics with Anti-Biofilm Activity RCS Advances, 2019, 9, 6770

2) Hagras, M.et al. Naphtylthiazoles: Targeting multidrug-resistance Staphylococcus aureus with biofilm disruption activities ACS Infect Dis, 2018, 4, 1679

3) ElAwamy, M. et al. Alkoxyphenylthiazoles with Broad-Spectrum Activity Against Multi-Drug Resistant Gram-Positive Bacterial Pathogens Eur. J. Med. Chem. 2018, 152, 318

4) Ngo, H. et al. Potent 1,2,4-triazinoindole-3-thioether inhibitors of the kanamycin resistance enzyme Eis from Mycobacterium tuberculosis ACS Infect Dis. 2018, 4, 1030

5) Hagras, M. et al. Investigating the Antibacterial Activity of Biphenylthiazoles Against Methicillin- and Vancomycin-Resistant Staphylococcus aureus (MRSA and VRSA) J. Med. Chem. 2017, 60, 4074





1) Towards Expanding the Antibacterial Spectrum of Phenylthiazole Antibiotics , ASRT

2) US-Egypt Joint Grant, Development of Next Generation Arylthiazoles for Combating Methicillin & Vancomycin Resistant Staphylococcus Aureus, STDF

3) Design and Synthesis of Liver Targeting Ribavirin Nanoparticle Conjugates; Science and Technology Development Fund (STDF-Egypt);

1) Egyptian State Encouragement Award in Medical Research

2) First-Class Excellence Medal from Presidential Office, August 2017

3) Young Arab Scientist (YAS) Prize in 2014 from TWAS-ARO (The World Academy of Sciences for the Advancement of Science in Developing Countries – Arab Regional Office).

4) Patents: US Patent App. 15/973,569, 2018; US Patent 9,801,861, 2017; US. PCT/US 2014/0121249 A1; US. PCT/US 2012/024706 and WO 2,012,109,573 A1 20120816.